High Resolution Fiber FISH:

• Construct a high-resolution physical map for specific regions
• Measure the physical distance between two markers
• Determine the order of markers along chromosomes with centromere-telomere orientation
• Determine the number of gene duplications/deletions in disease conditions
• Analyze the gene amplification array
• Map the translocation point
• Confirm mapping data generated from a radiation hybrids panel
• Determine the physical relationship between an identified novel gene and other genetic markers