Chromosome Localization

MDS will label and hybridize your DNA clones to map the sub-chromosomal position of your gene on normal metaphase chromosomes.

• Hybridize clones within a chromosomal walk in two colors to interphase nuclei to determine whether they are contiguous
• Deletion/amplification studies of a novel gene in tumor cell lines
• Novel gene or DNA fragment mapping on banded chromosomes (human, mouse and rat)
• Cross-species mapping utilizing alternate species cDNA probes. This can be accomplished, for example, by mapping a human locus using mouse, rat, other mammalian and even fly cDNA
• Evaluate novel gene relationships between human, mouse, rat and other species