Whole Genome Analysis

MDS offers microarray-based genotyping services for our clients’ genome-wide association studies such as chromosome copy number and allele specific analysis, linkage analyses and population genetic studies using the Human and Mouse Genome CGH microarrays. Following conducting whole genome analyses, we generally aim on targeted genes of interest. Typical applications include:

• Loss of and chromosome copy number
• Allele frequency quantification
• SNPs and mutations analyses
• Heterozygosity studies
• Cancer genetics
• Microbiology (microorganism typing and antibiotic resistance detection)

Individual SNP Genotyping

SNP profiling services are offered for pharmacokinetic, pharmacodynamic, safety, tolerability and efficiency outcomes through genotype/phenotype correlation analysis. To support these SNP profiling applications, MDS offers PCR/gel-based analyses (i.e. RFLP assays) and other genotyping services for a number of drug metabolism enzymes and other clinically relevant genes: