Host resistance challenge models (endpoints)

• Syngeneic tumor cells: MethA fibrosarcoma (growth and regression); B16 melanoma (lung burden)
• Bacterial models: Listeria monocytogenes (mortality); Streptococcus species (mortality)
• Viral models: Cytomegalovirus (viral load in salivary gland, lung, kidney, spleen, and liver)
• T-cells co-cultured with dendritic cells.
• Delayed-type hypersensitivity response to sheep RBCs or other such as chicken RBCs
• Skin rash
• Lymphadenopathy
• Urticaria (hives)
• IgE